Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 8/20 | 0.69 |
| ▸ | EGFR | P00533 | 6/20 | 0.68 |
| ▸ | RET | P07949 | 1/20 | 0.67 |
| ▸ | KIT | P10721 | 7/20 | 0.66 |
| ▸ | ABL1 | P00519 | 5/20 | 0.65 |
| ▸ | CSF1R | P07333 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254621 | 0.87 | KIT (0.77) | BRAFEGFRKITABL1 | |
| SCHEMBL13771723 | 0.86 | RET (0.83) | BRAFEGFRRETKITABL1 | |
| SCHEMBL31620875 | 0.86 | BRAF (0.66) | BRAFEGFRRETKITABL1 | |
| SCHEMBL17313595 | 0.85 | KIT (0.74) | BRAFEGFRKITABL1CSF1R | |
| SCHEMBL4906580 | 0.85 | CSF1R (0.72) | BRAFEGFRRETKITABL1 | |
| SCHEMBL13772031 | 0.85 | BRAF (0.79) | BRAFEGFRRETKITABL1 | |
| SCHEMBL28806373 | 0.84 | BRAF (0.75) | BRAFEGFRRETKITABL1 | |
| SCHEMBL13772005 | 0.84 | BRAF (0.69) | BRAFEGFRRETKITABL1 | |
| SCHEMBL13813464 | 0.84 | ABL1 (0.75) | BRAFEGFRKITABL1 | |
| SCHEMBL13813509 | 0.83 | ABL1 (0.73) | BRAFEGFRRETKITABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | disclosed |