Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 9/20 | 0.66 |
| ▸ | EGFR | P00533 | 7/20 | 0.66 |
| ▸ | KIT | P10721 | 7/20 | 0.64 |
| ▸ | RET | P07949 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 4/20 | 0.61 |
| ▸ | CSF1R | P07333 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806373 | 0.88 | BRAF (0.75) | BRAFEGFRKITRETABL1 | |
| SCHEMBL31620832 | 0.86 | BRAF (0.69) | BRAFEGFRKITRETABL1 | |
| SCHEMBL4254621 | 0.85 | KIT (0.77) | BRAFEGFRKITABL1 | |
| SCHEMBL17313595 | 0.84 | KIT (0.74) | BRAFEGFRKITABL1CSF1R | |
| SCHEMBL13771723 | 0.83 | RET (0.83) | BRAFEGFRKITRETABL1 | |
| SCHEMBL13813464 | 0.82 | ABL1 (0.75) | BRAFEGFRKITABL1 | |
| SCHEMBL13771814 | 0.81 | KIT (0.73) | BRAFEGFRKITRETABL1 | |
| SCHEMBL12871531 | 0.81 | KIT (0.84) | BRAFEGFRKITABL1 | |
| SCHEMBL10266107 | 0.81 | ABL1 (0.77) | BRAFEGFRKITRETABL1 | |
| SCHEMBL9610953 | 0.81 | ABL1 (0.77) | BRAFEGFRKITRETABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | disclosed |