SCHEMBL31621637

SCHEMBL31621637

CC(C)CC1Cc2nc(Cl)ccc2CN1C(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ABHD6 Q9BV23 1/20 0.42
▸ PTPN1 P18031 4/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ HDAC8 Q9BY41 4/20 0.35
▸ ESR2 Q92731 1/20 0.34
▸ NR1H2 P55055 1/20 0.34
▸ TSHR P16473 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ TACR1 P25103 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621656 1.00 ABHD6 (0.42) ABHD6PTPN1MEN1KMT2AHDAC8
SCHEMBL31621674 0.89 ABHD6 (0.40) ABHD6PTPN1MEN1KMT2AHDAC8
SCHEMBL31621644 0.89 ABHD6 (0.40) ABHD6PTPN1MEN1KMT2AHDAC8
SCHEMBL26914843 0.88 MEN1 (0.47) ABHD6PTPN1MEN1KMT2AHDAC8
SCHEMBL24602711 0.87 MEN1 (0.41) ABHD6PTPN1MEN1KMT2AHDAC8
SCHEMBL31621613 0.87 MEN1 (0.41) ABHD6PTPN1MEN1KMT2AHDAC8
SCHEMBL31621568 0.87 MEN1 (0.41) ABHD6PTPN1MEN1KMT2AHDAC8
SCHEMBL31621680 0.85 PTPN1 (0.42) PTPN1MEN1KMT2AHDAC8NR1H2
SCHEMBL31621608 0.85 PTPN1 (0.42) PTPN1MEN1KMT2AHDAC8NR1H2
SCHEMBL31621575 0.85 MEN1 (0.40) ABHD6PTPN1MEN1KMT2AHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703776-B Plasmin inhibitor, preparation method and application thereof 赛诺哈勃药业(成都)有限公司 2025-06-17 — — CN disclosed
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