Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 18/20 | 0.47 |
| ▸ | AKT3 | Q9Y243 | 17/20 | 0.47 |
| ▸ | AKT2 | P31751 | 12/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 3/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.41 |
| ▸ | RPS6KA1 | Q15418 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22307580 | 0.83 | AKT1 (0.50) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| SCHEMBL22308403 | 0.83 | AKT1 (0.50) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| SCHEMBL22308093 | 0.79 | AKT1 (0.49) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| SCHEMBL31594759 | 0.79 | AKT1 (0.49) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL25195685 | 0.78 | AKT1 (0.48) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL30460118 | 0.78 | AKT1 (0.48) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| SCHEMBL22308037 | 0.74 | AKT3 (0.46) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| SCHEMBL26544134 | 0.74 | AKT1 (0.57) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| SCHEMBL31628449 | 0.73 | AKT3 (0.61) | AKT1AKT3AKT2CYP3A4CYP1A2 | |
| SCHEMBL3939293 | 0.73 | HTR2A (0.36) | AKT1AKT3AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025124516-A1 | COMPOUND HAVING AKT KINASE-DEGRADING ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 南京正大天晴制药有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-120157686-A | Compound with AKT kinase degradation activity, preparation method and pharmaceutical application thereof | 南京正大天晴制药有限公司 | 2025-06-17 | — | — | CN | disclosed |