Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 20/20 | 0.48 |
| ▸ | WDR48 | Q8TAF3 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31623670 | 0.89 | USP1 (0.48) | USP1WDR48 | |
| SCHEMBL31623596 | 0.82 | USP1 (0.52) | USP1WDR48 | |
| SCHEMBL31557943 | 0.80 | USP1 (0.69) | USP1WDR48 | |
| SCHEMBL31623668 | 0.78 | USP1 (0.49) | USP1WDR48 | |
| SCHEMBL31623653 | 0.77 | USP1 (0.50) | USP1WDR48 | |
| SCHEMBL31623639 | 0.77 | USP1 (0.51) | USP1WDR48 | |
| SCHEMBL31624993 | 0.77 | USP1 (0.63) | USP1WDR48 | |
| SCHEMBL31623667 | 0.76 | USP1 (0.56) | USP1WDR48 | |
| SCHEMBL31623768 | 0.76 | USP1 (0.50) | USP1WDR48 | |
| SCHEMBL31623642 | 0.75 | USP1 (0.52) | USP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129076-A1 | PYRIDOPYRIMIDINE AND QUINAZOLINE DERIVATIVES AS USP1 INHIBITORS, COMPOSITIONS COMPRISING THEM AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-06-19 | — | — | WO | disclosed |