Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14798056 | 1.00 | BTK (0.47) | BTKJAK3JAK1JAK2USP30 | |
| SCHEMBL15143899 | 0.93 | BTK (0.57) | BTKJAK1JAK2USP30GPR119 | |
| SCHEMBL15710701 | 0.93 | BTK (0.57) | BTKJAK1JAK2USP30GPR119 | |
| SCHEMBL16320727 | 0.91 | BTK (0.51) | BTKJAK3JAK1JAK2USP30 | |
| SCHEMBL16320728 | 0.91 | BTK (0.51) | BTKJAK3JAK1JAK2USP30 | |
| SCHEMBL20480898 | 0.89 | BTK (0.42) | BTKJAK3JAK1JAK2ACHE | |
| SCHEMBL14797914 | 0.86 | GPR119 (0.44) | BTKJAK3JAK1JAK2USP30 | |
| SCHEMBL30760937 | 0.85 | JAK2 (0.45) | BTKJAK3JAK1JAK2USP30 | |
| SCHEMBL30760877 | 0.85 | JAK2 (0.45) | BTKJAK3JAK1JAK2USP30 | |
| SCHEMBL30760904 | 0.85 | JAK2 (0.45) | BTKJAK3JAK1JAK2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197401-A1 | PURINONE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197401-A1 | PURINONE DERIVATIVE | BTK, KIT, SYK | BTK 1/4885JAK3 78/4885JAK1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.