Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31631861 | 0.78 | TLR8 (0.48) | PIK3CATLR8KDM4EALDH1A1LMNA | |
| SCHEMBL15443926 | 0.77 | DYRK1A (0.36) | — | |
| SCHEMBL18134204 | 0.77 | CCNA2 (0.44) | PIK3CACCNA2CDK2CCNA1MAPK1 | |
| SCHEMBL9287284 | 0.77 | CCNA2 (0.44) | PIK3CACCNA2CDK2CCNA1TLR8 | |
| SCHEMBL10860584 | 0.74 | CCNA2 (0.41) | PIK3CACCNA2CDK2CCNA1MAPK1 | |
| SCHEMBL4104572 | 0.74 | CCNA2 (0.41) | PIK3CACCNA2CDK2CCNA1TLR8 | |
| SCHEMBL28221808 | 0.74 | CCNA2 (0.41) | PIK3CACCNA2CDK2CCNA1TLR8 | |
| SCHEMBL26978230 | 0.74 | ALDH1A1 (0.51) | PIK3CACCNA2CDK2CCNA1TLR8 | |
| SCHEMBL12599922 | 0.74 | CYP1A2 (0.41) | ALDH1A1CYP1A2 | |
| SCHEMBL21359097 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |