Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31631810 | 0.86 | F2RL1 (0.37) | F2RL1GRIN2BGRIN1GRM2CYP3A4 | |
| SCHEMBL31631772 | 0.85 | F2RL1 (0.37) | F2RL1GRIN2BGRIN1GRM2CYP3A4 | |
| SCHEMBL31631865 | 0.83 | F2RL1 (0.35) | F2RL1PTGS2PTGS1TP53S1PR1 | |
| SCHEMBL31631744 | 0.83 | F2RL1 (0.35) | F2RL1PTGS2PTGS1TP53S1PR1 | |
| SCHEMBL31631840 | 0.83 | HDAC6 (0.32) | GRIN2BGRIN1HDAC6MAPT | |
| SCHEMBL31629499 | 0.80 | F2RL1 (0.35) | F2RL1PTGS2PTGS1CYP3A4CYP2D6 | |
| SCHEMBL31629501 | 0.80 | F2RL1 (0.35) | F2RL1PTGS2PTGS1CYP3A4CYP2D6 | |
| SCHEMBL31631896 | 0.79 | NPC1 (0.37) | GRIN2BGRIN1PTGS2ALOX5APFEN1 | |
| SCHEMBL31629313 | 0.79 | ALOX5AP (0.33) | F2RL1GRIN2BGRIN1PTGS2ALOX5AP | |
| SCHEMBL31631830 | 0.77 | F2RL1 (0.35) | F2RL1CYP3A4CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |