Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31629499 | 1.00 | F2RL1 (0.35) | F2RL1PTGS2ICMTDGAT1PTPN1 | |
| SCHEMBL31631795 | 0.85 | F2RL1 (0.35) | F2RL1DGAT1PTPN1KLKB1CYP3A4 | |
| SCHEMBL31629158 | 0.85 | F2RL1 (0.35) | F2RL1DGAT1KLKB1CYP3A4CYP2D6 | |
| SCHEMBL31629429 | 0.83 | DGAT1 (0.31) | F2RL1PTGS2DGAT1KLKB1 | |
| SCHEMBL31631865 | 0.81 | F2RL1 (0.35) | F2RL1PTGS2TRPV1PTGS1 | |
| SCHEMBL31631744 | 0.81 | F2RL1 (0.35) | F2RL1PTGS2TRPV1PTGS1 | |
| SCHEMBL31631906 | 0.80 | F2RL1 (0.37) | F2RL1PTGS2PTGS1CYP3A4CYP2D6 | |
| SCHEMBL31628980 | 0.79 | KMT2A (0.34) | PTGS2DGAT1PTPN1KLKB1 | |
| SCHEMBL31629440 | 0.76 | DGAT1 (0.36) | F2RL1DGAT1 | |
| SCHEMBL31629110 | 0.75 | DGAT1 (0.33) | F2RL1DGAT1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125666-A1 | SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |