Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTR | Q99707 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 4/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31633001 | 0.85 | MTR (0.43) | MTRCHRM2CHRM3SCN1ASCN5A | |
| SCHEMBL31633003 | 0.76 | MTR (0.46) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL31633102 | 0.76 | SCN1A (0.42) | MTRCHRM2CHRM3SCN1ASCN5A | |
| SCHEMBL31632774 | 0.74 | MTR (0.46) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL31632990 | 0.73 | MTR (0.46) | MTRSCN1ASCN5ASCN9APARP1 | |
| SCHEMBL31632897 | 0.73 | GRM2 (0.46) | CYP2D6 | |
| SCHEMBL3101936 | 0.72 | SSTR5 (0.50) | MTRSCN1ASCN5ASCN9A | |
| SCHEMBL6191353 | 0.72 | MTR (0.66) | MTRCHRM2CHRM3SCN1ASCN5A | |
| SCHEMBL31633164 | 0.72 | HRH1 (0.45) | CYP2D6 | |
| SCHEMBL31633194 | 0.72 | GRM2 (0.40) | BDKRB1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129167-A1 | INHIBITORS OF THE SURFACE EXPRESSION OF THE VOLTAGE-GATED SODIUM ION CHANNEL 1.7 (NAV1.7) AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |