Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120345 | 1.00 | SCN9A (0.54) | SCN9AIDO1TDO2KDM4CDGAT2 | |
| SCHEMBL31633145 | 0.86 | SCN9A (0.53) | SCN9AIDO1TDO2DGAT2GSK3B | |
| SCHEMBL121474 | 0.86 | SCN9A (0.68) | SCN9ABRD4S1PR1ASH1LSCN5A | |
| SCHEMBL121650 | 0.85 | IDO1 (0.58) | SCN9AIDO1TDO2S1PR1SCN5A | |
| SCHEMBL121689 | 0.84 | SCN9A (0.72) | SCN9ADGAT2S1PR1SCN5A | |
| SCHEMBL31632863 | 0.78 | IDO1 (0.44) | SCN9AIDO1TDO2GSK3BBRD4 | |
| SCHEMBL121389 | 0.77 | SCN9A (0.70) | SCN9AS1PR1SCN5A | |
| SCHEMBL19475709 | 0.77 | SCN9A (0.70) | SCN9AIDO1TDO2SCN5A | |
| SCHEMBL122571 | 0.77 | SCN9A (0.67) | SCN9ABRD4S1PR1ASH1LSCN5A | |
| SCHEMBL6840324 | 0.77 | SNCA (0.50) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129167-A1 | INHIBITORS OF THE SURFACE EXPRESSION OF THE VOLTAGE-GATED SODIUM ION CHANNEL 1.7 (NAV1.7) AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |