Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15958962 | 0.85 | IDO1 (0.53) | IDO1TDO2GSK3BPRKCAKDM4E | |
| SCHEMBL22159339 | 0.85 | SCN9A (0.51) | IDO1TDO2GSK3BBRD4KDM4E | |
| SCHEMBL31632773 | 0.78 | SCN9A (0.44) | IDO1TDO2BRD4KDM4EALDH1A1 | |
| SCHEMBL31633178 | 0.78 | SCN9A (0.54) | IDO1TDO2GSK3BPRKCABRD4 | |
| SCHEMBL120345 | 0.78 | SCN9A (0.54) | IDO1TDO2GSK3BPRKCABRD4 | |
| SCHEMBL31632917 | 0.75 | PTGER1 (0.39) | KDM4EALDH1A1SCN9ACYP2A6 | |
| SCHEMBL31633145 | 0.75 | SCN9A (0.53) | IDO1TDO2GSK3BPRKCABRD4 | |
| SCHEMBL694131 | 0.73 | ASH1L (0.41) | IDO1TDO2GSK3BPRKCABRD4 | |
| SCHEMBL13038411 | 0.73 | PDE3B (0.45) | BRD4ALDH1A1 | |
| SCHEMBL19831270 | 0.70 | CYP2A6 (0.50) | KDM4EALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129167-A1 | INHIBITORS OF THE SURFACE EXPRESSION OF THE VOLTAGE-GATED SODIUM ION CHANNEL 1.7 (NAV1.7) AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |