SCHEMBL31635537

SCHEMBL31635537

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)C2CN(c3cccc(F)c3)C2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 4/20 0.43
▸ UCHL1 P09936 2/20 0.40
▸ NOTUM Q6P988 1/20 0.37
▸ NR3C2 P08235 1/20 0.35
▸ PIK3CD O00329 1/20 0.34
▸ SLC6A9 P48067 1/20 0.34
▸ KCNH2 Q12809 1/20 0.34
▸ NTRK1 P04629 1/20 0.34
▸ NTRK3 Q16288 1/20 0.34
▸ NTRK2 Q16620 1/20 0.34
▸ BRD4 O60885 1/20 0.34
▸ BRD2 P25440 1/20 0.34
▸ BRD3 Q15059 1/20 0.34
▸ CYP11B2 P19099 2/20 0.33
▸ SCD O00767 1/20 0.33
▸ RPS6KB1 P23443 1/20 0.33
▸ AKT1 P31749 1/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ MAPT P10636 1/20 0.33
▸ HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774512 0.92 USP30 (0.45) USP30UCHL1NOTUMPIK3CDKCNH2
SCHEMBL30774432 0.90 USP30 (0.42) USP30UCHL1NR3C2CYP11B2MEN1
SCHEMBL30774886 0.89 USP30 (0.45) USP30UCHL1CYP11B2MEN1CYP11B1
SCHEMBL31635534 0.87 USP30 (0.42) USP30UCHL1CYP11B2HPGDCYP11B1
SCHEMBL30774590 0.86 USP30 (0.42) USP30UCHL1CYP11B2HPGDCYP11B1
SCHEMBL30774439 0.85 CHRM1 (0.46) USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774783 0.83 HTR6 (0.38) NR3C2PIK3CDKCNH2NTRK1NTRK3
SCHEMBL30774644 0.83 USP30 (0.46) USP30UCHL1MEN1HPGDKMT2A
SCHEMBL30774398 0.83 USP30 (0.46) USP30UCHL1MEN1HPGDKMT2A
SCHEMBL30774894 0.83 CYP3A4 (0.42) USP30UCHL1NR3C2CYP11B2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 USP30 728/4885UCHL1 1728/4885NOTUM 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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