Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | SCD | O00767 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568136 | 0.91 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2DYRK1ADYRK1B | |
| SCHEMBL31637674 | 0.89 | HSD17B10 (0.61) | HTTNPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL23256883 | 0.87 | DYRK1A (0.66) | HTTNPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL21568149 | 0.87 | DYRK1A (0.53) | HTTNPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL21568128 | 0.87 | RAB9A (0.73) | HTTNPC1RAB9ASMN1; SMN2SCD | |
| SCHEMBL21568324 | 0.85 | DYRK1A (0.58) | HTTNPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL21568954 | 0.85 | DYRK1A (0.66) | PIK3CGNPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL23256872 | 0.83 | HSD17B10 (0.61) | HTTNPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL21568062 | 0.83 | DYRK1A (0.58) | HTTNPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL23256882 | 0.83 | DYRK1A (0.58) | HTTNPC1RAB9ASMN1; SMN2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025136887-A1 | COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-06-26 | — | — | WO | disclosed |