Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | NRAS | P01111 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30698310 | 0.87 | ALK (0.35) | CDK4CCND1CCND3CDK6PIK3CD | |
| SCHEMBL31000072 | 0.85 | CDK4 (0.45) | CDK4CCND1CCND3CDK6ALK | |
| SCHEMBL31639355 | 0.84 | DNMT3A (0.34) | CDK4CCND1CCND3CDK6ALK | |
| SCHEMBL31739613 | 0.84 | ALK (0.35) | CDK4CCND1CCND3CDK6PIK3CD | |
| SCHEMBL30698359 | 0.84 | ALK (0.35) | CDK4CCND1CCND3CDK6PIK3CD | |
| SCHEMBL30698291 | 0.84 | PIK3CD (0.40) | PIK3CDNTRK1ALKDNMT3ANSD2 | |
| SCHEMBL31000195 | 0.83 | CFTR (0.36) | CDK4CCND1CCND3CDK6USP30 | |
| SCHEMBL31639210 | 0.83 | USP30 (0.38) | CDK4CCND1CCND3CDK6PIK3CD | |
| SCHEMBL30698314 | 0.82 | ALK (0.34) | CDK4CCND1CCND3CDK6PIK3CD | |
| SCHEMBL31639205 | 0.81 | NRAS (0.44) | NRASFLT3CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |