Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | NRAS | P01111 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639307 | 0.92 | TBK1 (0.38) | USP30PIK3CAPIK3R1ALKNSD2 | |
| SCHEMBL30698310 | 0.88 | ALK (0.35) | ALKCDK4CCND1CCND3CDK6 | |
| SCHEMBL30698314 | 0.87 | ALK (0.34) | PIK3CAALKCDK4CCND1CCND3 | |
| SCHEMBL31000188 | 0.85 | PIK3CA (0.40) | USP30PIK3CAPIK3R1ALKCDK4 | |
| SCHEMBL31000187 | 0.85 | PIK3CA (0.40) | USP30PIK3CAPIK3R1ALKCDK4 | |
| SCHEMBL31739613 | 0.85 | ALK (0.35) | USP30PIK3CAALKPIK3CGCDK4 | |
| SCHEMBL31639084 | 0.83 | CDK4 (0.36) | USP30PIK3CAALKCDK4CCND1 | |
| SCHEMBL30698359 | 0.82 | ALK (0.35) | USP30PIK3CAPIK3R1ALKCDK4 | |
| SCHEMBL31000192 | 0.82 | CDK4 (0.42) | ALKCDK4CCND1CCND3CDK6 | |
| SCHEMBL31639195 | 0.82 | FLT3 (0.46) | PIK3CAMTORNRASFLT3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |