Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | SRC | P12931 | 4/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | HCK | P08631 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.49 |
| ▸ | PRKDC | P78527 | 2/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.49 |
| ▸ | RET | P07949 | 10/20 | 0.45 |
| ▸ | BTK | Q06187 | 5/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639974 | 0.90 | RET (0.47) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31639990 | 0.83 | TGFBR1 (0.41) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31639321 | 0.83 | RET (0.41) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31639786 | 0.82 | RET (0.48) | KDREGFRSRCPIK3CDABL1 | |
| Hydrochloric Acid SCHEMBL31640040 | 0.81 | RET (0.51) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31640437 | 0.81 | SRC (0.42) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31639403 | 0.81 | SRC (0.42) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31640192 | 0.80 | RET (0.48) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31639555 | 0.80 | TGFBR1 (0.39) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL31639556 | 0.79 | RET (0.48) | KDREGFRSRCPIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |