Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639550 | 1.00 | NR1H2 (0.45) | NR1H2POLBGRM5CYP11B2CKS1B | |
| SCHEMBL2160148 | 0.83 | MEN1 (0.46) | NR1H2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30487317 | 0.82 | USP30 (0.44) | NR1H2GRM5MEN1KMT2AMAPT | |
| SCHEMBL2261033 | 0.78 | NR1H2 (0.41) | NR1H2GRM5CYP11B2MAPTPIK3R1 | |
| SCHEMBL31639966 | 0.78 | CYP11B2 (0.42) | NR1H2POLBGRM5CYP11B2CKS1B | |
| SCHEMBL13275649 | 0.76 | CYP11B2 (0.54) | GRM5CYP11B2GPR119 | |
| SCHEMBL30872427 | 0.74 | NR1H2 (0.43) | NR1H2GRM5CYP11B2MEN1KMT2A | |
| SCHEMBL30872426 | 0.74 | NR1H2 (0.43) | NR1H2GRM5CYP11B2MEN1KMT2A | |
| SCHEMBL12217740 | 0.74 | NR1H2 (0.48) | NR1H2GRM5MEN1KMT2AMAPT | |
| SCHEMBL17304324 | 0.74 | NR1H2 (0.48) | NR1H2GRM5MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |