Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 19/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | FGR | P09769 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639668 | 0.92 | RET (0.44) | RETCYP1A2HCKFGRRPS6KB1 | |
| SCHEMBL31640323 | 0.85 | RET (0.54) | RETCYP1A2HCKFGRRPS6KB1 | |
| SCHEMBL31639492 | 0.85 | RET (0.40) | RETCYP1A2HCKFGRRPS6KB1 | |
| SCHEMBL31639606 | 0.81 | SRC (0.47) | RETCYP1A2HCKFGRRPS6KB1 | |
| SCHEMBL31639823 | 0.81 | RET (0.60) | RETCYP1A2HCKFGRRPS6KB1 | |
| SCHEMBL31640565 | 0.80 | RET (0.53) | RETHCKRPS6KB1FLT4KDR | |
| SCHEMBL31639447 | 0.78 | RET (0.57) | RETCYP1A2HCKFGRRPS6KB1 | |
| SCHEMBL31639653 | 0.78 | RET (0.41) | RET | |
| SCHEMBL31639514 | 0.77 | RET (0.68) | RETCYP1A2HCKFGRRPS6KB1 | |
| SCHEMBL31639265 | 0.77 | RET (0.62) | RETCYP1A2HCKFGRRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |