Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 7/20 | 0.53 |
| ▸ | SRC | P12931 | 12/20 | 0.46 |
| ▸ | KDR | P35968 | 12/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
| ▸ | FER | P16591 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639606 | 0.85 | SRC (0.47) | RETSRCKDRLCKPLK4 | |
| SCHEMBL31640083 | 0.84 | RET (0.57) | RETSRCKDRLCKCDC7 | |
| SCHEMBL31639823 | 0.83 | RET (0.60) | RETSRCKDRRPS6KB1FLT4 | |
| SCHEMBL31639492 | 0.82 | RET (0.40) | RETKDRRPS6KB1FLT4HCK | |
| SCHEMBL31639668 | 0.82 | RET (0.44) | RETKDRRPS6KB1FLT4HCK | |
| SCHEMBL31639633 | 0.80 | RET (0.41) | RETKDRRPS6KB1FLT4HCK | |
| SCHEMBL31639265 | 0.80 | RET (0.62) | RETSRCKDRRPS6KB1FLT4 | |
| SCHEMBL31640064 | 0.80 | RET (0.62) | RETSRCKDRLCKPIK3CD | |
| SCHEMBL31639663 | 0.74 | RET (0.59) | RETSRCKDRLCKEGFR | |
| SCHEMBL31639920 | 0.74 | RET (0.73) | RETSRCKDRLCKRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |