Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 10/20 | 0.39 |
| ▸ | SRC | P12931 | 10/20 | 0.39 |
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | ABL1 | P00519 | 6/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.39 |
| ▸ | FYN | P06241 | 3/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | YES1 | P07947 | 2/20 | 0.39 |
| ▸ | LYN | P07948 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | FRK | P42685 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31640038 | 0.93 | RET (0.40) | RETSRCKDRABL1RIPK2 | |
| SCHEMBL31639568 | 0.89 | RET (0.43) | RETSRCKDRABL1RIPK2 | |
| Hydrochloric Acid SCHEMBL31639825 | 0.88 | SRC (0.43) | RETSRCKDRABL1RIPK2 | |
| SCHEMBL31639658 | 0.88 | RET (0.38) | RETSRCKDRABL1RIPK2 | |
| SCHEMBL31641098 | 0.87 | RET (0.49) | RETKDRRPS6KB1FLT4CYP1A2 | |
| SCHEMBL31640331 | 0.86 | RET (0.42) | RETSRCKDRABL1RIPK2 | |
| SCHEMBL31639980 | 0.86 | SRC (0.42) | RETSRCKDRABL1RIPK2 | |
| SCHEMBL31639828 | 0.85 | TGFBR1 (0.39) | RETSRCKDRABL1RIPK2 | |
| SCHEMBL31639614 | 0.83 | RET (0.44) | RETSRCKDRABL1RIPK2 | |
| SCHEMBL31640604 | 0.83 | RET (0.47) | RETKDRRPS6KB1FLT4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |