SCHEMBL31639986

SCHEMBL31639986

O=C1CCC(Oc2cc(F)c(N3CCN(CC4CCNCC4)CC3)c(F)c2)C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 15/20 0.43
▸ DDB1 Q16531 13/20 0.43
▸ DRD2 P14416 1/20 0.35
▸ IKZF3 Q9UKT9 1/20 0.34
▸ FFAR4 Q5NUL3 1/20 0.33
▸ CACNA2D1 P54289 1/20 0.32
▸ CACNA1B Q00975 1/20 0.32
▸ CACNB1 Q02641 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31639696 0.86 DDB1 (0.49) CRBNDDB1
SCHEMBL31313237 0.81 CRBN (0.50) CRBNDDB1FFAR4
SCHEMBL31639532 0.80 DDB1 (0.52) CRBNDDB1
Hydrochloric Acid SCHEMBL31640162 0.79 DDB1 (0.51) CRBNDDB1
SCHEMBL31447862 0.78 CRBN (0.47) CRBNDDB1DRD2IKZF3
SCHEMBL31312861 0.75 CRBN (0.49) CRBNDDB1
SCHEMBL25447095 0.75 CRBN (0.51) CRBNDDB1
SCHEMBL31447664 0.74 CRBN (0.62) CRBNDDB1
SCHEMBL31447863 0.74 DDB1 (0.49) CRBNDDB1
SCHEMBL31639622 0.73 DDB1 (0.57) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137605-A1 COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR C4 THERAPEUTICS, INC. (US) 2025-06-26 — — WO disclosed
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