SCHEMBL31642641

SCHEMBL31642641

N#CC[C@H]1C[C@H]1c1c(Cl)cc2c(cnn2[C@H]2CCCCO2)c1Br

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 0.35
▸ RXRB P28702 1/20 0.35
▸ RXRG P48443 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30922619 0.87 RXRA (0.41) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31642625 0.87 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31642702 0.87 RXRA (0.41) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31642584 0.87 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL24535801 0.83 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31642882 0.83 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31127821 0.83 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31527282 0.83 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31127777 0.83 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA
SCHEMBL31643015 0.83 RXRA (0.37) RXRARXRBRXRGALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025136346-A1 INDAZOLE CONTAINING COMPOUNDS AND METHODS OF USE AMGEN INC. (US) 2025-06-26 — — WO disclosed
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