Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.45 |
| ▸ | CSF1R | P07333 | 10/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937358 | 0.90 | KIT (0.56) | KITCSF1RCYP2C19 | |
| SCHEMBL31157982 | 0.90 | KIT (0.56) | KITCSF1RCYP2C19 | |
| SCHEMBL3173458 | 0.90 | KIT (0.55) | KITCSF1RCYP2C19 | |
| SCHEMBL2937803 | 0.89 | CSF1R (0.43) | KITCSF1R | |
| SCHEMBL14383789 | 0.89 | CSF1R (0.48) | KITCSF1R | |
| SCHEMBL2940149 | 0.89 | KIT (0.45) | KITCSF1RCYP2C19 | |
| SCHEMBL2942364 | 0.88 | CSF1R (0.51) | KITCSF1RCYP2C19 | |
| SCHEMBL5647027 | 0.87 | CSF1R (0.45) | KITCSF1R | |
| SCHEMBL1857867 | 0.87 | CSF1R (0.59) | KITCSF1R | |
| SCHEMBL4231785 | 0.86 | CSF1R (0.45) | KITCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645755-B2 | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICAL N.V. (BE) | 2010-01-12 | — | — | US | disclosed |
| US-7645755-B2 | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICAL N.V. (BE) | 2010-01-12 | — | — | US | disclosed |
| US-20060189623-A1 | Inhibitors of c-fms kinase | ILLIG CARL R | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189623-A1 | Inhibitors of c-fms kinase | MUSK, TYK2, FES | KIT 125/4885CSF1R 34/4885CYP2C19 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.