Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16387388 | 0.89 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL31260368 | 0.87 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL31260325 | 0.86 | TSHR (0.50) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL31260359 | 0.84 | CYP3A4 (0.48) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL26672534 | 0.84 | CYP3A4 (0.46) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL31260406 | 0.83 | CYP3A4 (0.47) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL31644838 | 0.83 | CYP3A4 (0.51) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL31260378 | 0.82 | TSHR (0.48) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL21111957 | 0.82 | TSHR (0.50) | CYP3A4TSHRTDP1ATMLMNA | |
| SCHEMBL13845815 | 0.81 | TSHR (0.52) | CYP3A4TSHRTDP1ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132542-A1 | MACROCYCLIC OREXIN AGONISTS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-26 | — | — | WO | disclosed |