Sugi Predict

Sugi Predict / Compounds / SCHEMBL31647883

SCHEMBL31647883

SCHEMBL31647883

CCCCCNc1ccc2cc(Br)c(N)nc2n1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 4/20 0.43
▸ ABL1 P00519 1/20 0.39
▸ HCAR3 P49019 1/20 0.37
▸ DNM2 P50570 8/20 0.37
▸ TLR7 Q9NYK1 1/20 0.36
▸ FGFR1 P11362 1/20 0.36
▸ SOAT1 P35610 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31648525 0.79 TLR8 (0.49) TLR8HCAR3DNM2SOAT1
SCHEMBL31647858 0.78 ABL1 (0.34) TLR8ABL1HCAR3DNM2SOAT1
SCHEMBL16019053 0.77 TLR8 (0.46) TLR8HCAR3DNM2
SCHEMBL31647879 0.76 FGFR1 (0.52) TLR8FGFR1
SCHEMBL31648041 0.75 TLR8 (0.41) TLR8TLR7SOAT1
SCHEMBL31648433 0.74 FGFR1 (0.45) HCAR3FGFR1
SCHEMBL16019055 0.72 TLR8 (0.51) TLR8HCAR3
SCHEMBL547309 0.69 TLR8 (0.48) TLR8HCAR3DNM2TLR7SOAT1
SCHEMBL16019054 0.68 HRH3 (0.50) TLR8
SCHEMBL11498443 0.67 TLR8 (0.45) TLR8ABL1HCAR3DNM2SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133660-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
WO-2025132449-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
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