Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 6/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31648260 | 0.80 | LMNA (0.41) | EPHX2LMNATSHRNPSR1CNR1 | |
| SCHEMBL31648461 | 0.73 | POLQ (0.47) | LMNATSHRNPSR1POLQALDH1A1 | |
| SCHEMBL31648333 | 0.71 | POLQ (0.42) | LMNATSHRNPSR1POLQALDH1A1 | |
| SCHEMBL14489168 | 0.71 | LMNA (0.38) | LMNATSHRNPSR1POLQALDH1A1 | |
| SCHEMBL31648570 | 0.71 | EPHX2 (0.44) | EPHX2LMNATSHRNPSR1CNR1 | |
| SCHEMBL24076290 | 0.69 | AKR1B1 (0.46) | CNR1PTGDR2 | |
| SCHEMBL31648724 | 0.68 | POLQ (0.41) | LMNATSHRNPSR1POLQPTGDR2 | |
| SCHEMBL31648588 | 0.68 | GRIN1 (0.45) | EPHX2LMNATSHRNPSR1ALDH1A1 | |
| SCHEMBL14555664 | 0.68 | POLB (0.58) | GAA | |
| SCHEMBL14484375 | 0.67 | POLQ (0.62) | LMNATSHRNPSR1POLQALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |