SCHEMBL31648337

SCHEMBL31648337

C#CCCCNc1ncc2cc(-c3ccccc3OC)c(NC(=O)NC(C)(C)C)nc2n1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 20/20 0.65
▸ SRC P12931 8/20 0.65
▸ PDGFRB P09619 3/20 0.65
▸ PDGFRA P16234 3/20 0.65
▸ FGFR2 P21802 8/20 0.59
▸ FGFR4 P22455 8/20 0.59
▸ FGFR3 P22607 8/20 0.59
▸ FLT1 P17948 3/20 0.59
▸ FLT4 P35916 3/20 0.59
▸ KDR P35968 3/20 0.59
▸ EGFR P00533 4/20 0.56
▸ PRKD3 O94806 2/20 0.55
▸ PRKCG P05129 2/20 0.55
▸ PRKCB P05771 2/20 0.55
▸ PRKCA P17252 2/20 0.55
▸ PRKCH P24723 2/20 0.55
▸ PRKCI P41743 2/20 0.55
▸ PRKCE Q02156 2/20 0.55
▸ PRKCQ Q04759 2/20 0.55
▸ PRKCZ Q05513 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15047128 0.85 FGFR1 (0.81) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL15047127 0.83 FGFR1 (0.80) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL31648009 0.80 FGFR1 (0.78) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL8130201 0.79 FGFR1 (1.00) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL31648278 0.78 FGFR1 (0.46) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL31647907 0.77 FGFR1 (0.75) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL31647777 0.76 FGFR1 (0.60) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL31648262 0.75 FGFR1 (0.76) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL12863160 0.74 FGFR1 (0.62) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL31648124 0.74 FGFR1 (0.39) FGFR1FGFR2FGFR4FGFR3PRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133660-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
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