SCHEMBL31648124

SCHEMBL31648124

C#CCCCNc1ncc2cc(-c3ccccc3OC)c([N+](=O)[O-])cc2n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 2/20 0.39
▸ FGFR2 P21802 2/20 0.39
▸ FGFR4 P22455 2/20 0.39
▸ FGFR3 P22607 2/20 0.39
▸ PRKCQ Q04759 3/20 0.38
▸ PTK2 Q05397 1/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.37
▸ RPS6KB2 Q9UBS0 1/20 0.36
▸ MAPT P10636 5/20 0.36
▸ PLK1 P53350 1/20 0.36
▸ S1PR1 P21453 1/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ PIN1 Q13526 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31648136 0.83 FGFR4 (0.44) FGFR1FGFR2FGFR4FGFR3RPS6KB2
SCHEMBL31648407 0.76 PIN1 (0.57) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL31648337 0.74 FGFR1 (0.65) FGFR1FGFR2FGFR4FGFR3PRKCQ
SCHEMBL31647960 0.69 FGFR1 (0.47) FGFR1FGFR2FGFR4FGFR3KMT2A
SCHEMBL1517226 0.68 RXFP1 (0.43) FGFR1FGFR2FGFR4FGFR3PTK2
SCHEMBL31648077 0.68 FGFR1 (0.43) FGFR1FGFR2FGFR4FGFR3KMT2A
SCHEMBL31647792 0.66 FGFR1 (0.47) FGFR1FGFR2FGFR4FGFR3KMT2A
SCHEMBL31648264 0.66 FGFR1 (0.59) FGFR1FGFR2FGFR4FGFR3KMT2A
SCHEMBL1517338 0.64 FGFR2 (0.46) FGFR1FGFR2FGFR4FGFR3
SCHEMBL1516980 0.64 PDGFRB (0.44) FGFR1FGFR4MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132449-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
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