Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649275 | 1.00 | KDM4E (0.36) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31649133 | 0.92 | KDM4E (0.32) | KDM4ETDP1 | |
| SCHEMBL31737401 | 0.91 | KDM4E (0.37) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31737397 | 0.91 | KDM4E (0.36) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31737567 | 0.89 | GRK6 (0.37) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31649114 | 0.89 | KDM4E (0.35) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31649112 | 0.88 | MAPT (0.37) | KDM4EADRB2ADRB1HCRTR1HCRTR2 | |
| SCHEMBL31737838 | 0.88 | CAMK2D (0.36) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31649208 | 0.86 | KDM4E (0.37) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31649019 | 0.86 | RXFP1 (0.43) | KDM4EMEN1POLBKMT2APTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242908-A2 | NOVEL COMPOUNDS | GENOME THERAPEUTICS LTD (GB) | 2025-11-27 | — | — | WO | disclosed |
| WO-2025133338-A1 | QUINOLONE DERIVATVES AGAINST CANCER | GENOME THERAPEUTICS LTD (GB) | 2025-06-26 | — | — | WO | disclosed |