Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.57 |
| ▸ | DPP4 | P27487 | 16/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.43 |
| ▸ | FAP | Q12884 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649050 | 0.84 | DPP7 (0.60) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL31649359 | 0.79 | DPP7 (0.55) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL31649201 | 0.79 | DPP7 (0.55) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL15832763 | 0.77 | DPP4 (0.48) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL7293351 | 0.77 | ACE (0.57) | DPP4RAB9A | |
| SCHEMBL7293358 | 0.77 | ACE (0.57) | DPP4RAB9A | |
| SCHEMBL14392392 | 0.75 | DPP4 (0.65) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL8277346 | 0.75 | DPP4 (0.65) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL938422 | 0.75 | NPC1 (0.50) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL15224218 | 0.74 | NPC1 (0.48) | DPP7DPP4DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |