SCHEMBL31649050

SCHEMBL31649050

N[C@H](CO)C(=O)N1CCC[C@H]2CCCC[C@@H]21

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 10/20 0.60
▸ DPP4 P27487 15/20 0.43
▸ DPP8 Q6V1X1 7/20 0.43
▸ DPP9 Q86TI2 7/20 0.43
▸ FAP Q12884 6/20 0.43
▸ NPC1 O15118 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31649082 0.84 DPP7 (0.57) DPP7DPP4DPP8DPP9FAP
SCHEMBL31649201 0.82 DPP7 (0.55) DPP7DPP4DPP8DPP9FAP
SCHEMBL31649359 0.82 DPP7 (0.55) DPP7DPP4DPP8DPP9FAP
SCHEMBL31649426 0.80 DPP7 (0.42) DPP7DPP4
SCHEMBL12308338 0.76 DPP7 (0.46) DPP7DPP4DPP8DPP9FAP
SCHEMBL11282748 0.76 DPP7 (0.46) DPP7DPP4DPP8DPP9FAP
SCHEMBL29380436 0.75 ACE (0.56) DPP4RAB9A
SCHEMBL29405754 0.75 ACE (0.56) DPP4RAB9A
SCHEMBL30203686 0.75 DPP4 (0.44) DPP7DPP4DPP8DPP9FAP
SCHEMBL31649045 0.75 DPP7 (0.47) DPP7DPP4DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132943-A1 DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS BREAKPOINT THERAPEUTICS GMBH (DE) 2025-06-26 — — WO disclosed
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