Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31652004 | 0.86 | TLR9 (0.51) | SMPD3TLR9TLR7GPR119CKS1B | |
| SCHEMBL17310150 | 0.86 | TLR9 (0.51) | SMPD3TLR9TLR7GPR119CKS1B | |
| SCHEMBL31651790 | 0.86 | TLR9 (0.51) | SMPD3TLR9TLR7GPR119CKS1B | |
| SCHEMBL31651709 | 0.84 | TLR9 (0.49) | SMPD3TLR9TLR7GPR119CKS1B | |
| SCHEMBL31652099 | 0.82 | TLR9 (0.54) | SMPD3TLR9TLR7GPR119CKS1B | |
| SCHEMBL31651803 | 0.82 | TLR9 (0.47) | SMPD3TLR9TLR7GPR119CKS1B | |
| SCHEMBL31651781 | 0.80 | TLR9 (0.49) | SMPD3TLR9TLR7GPR119CKS1B | |
| SCHEMBL11359476 | 0.80 | POLB (0.55) | TLR9TLR7GPR119CKS1BSKP1 | |
| SCHEMBL31651630 | 0.80 | TLR9 (0.52) | SMPD3TLR9TLR7GPR119SUV39H2 | |
| SCHEMBL31651640 | 0.80 | TLR9 (0.52) | SMPD3TLR9TLR7GPR119SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | STAT6, STAT5B, STAT5A | SMPD3 2793/4885TLR9 301/4885TLR7 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.