Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.51 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.48 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310150 | 1.00 | TLR9 (0.51) | TLR9SMPD3SUV39H2GBA1GPR119 | |
| SCHEMBL15401487 | 0.88 | PDE4B (0.42) | TLR9SMPD3SUV39H2GBA1GPR119 | |
| SCHEMBL31651998 | 0.86 | SMPD3 (0.53) | TLR9SMPD3SUV39H2GBA1GPR119 | |
| SCHEMBL31651790 | 0.85 | TLR9 (0.51) | TLR9SMPD3SUV39H2GBA1GPR119 | |
| SCHEMBL24485823 | 0.84 | GBA1 (0.47) | TLR9GBA1GPR119CKS1BSKP1 | |
| SCHEMBL31651709 | 0.83 | TLR9 (0.49) | TLR9SMPD3SUV39H2GBA1GPR119 | |
| SCHEMBL17310111 | 0.82 | GPR119 (0.45) | TLR9GPR119ALDH1A1CFTR | |
| SCHEMBL17310110 | 0.82 | GPR119 (0.45) | TLR9GPR119ALDH1A1CFTR | |
| SCHEMBL20919447 | 0.81 | BACE1 (0.46) | TLR9SMPD3SUV39H2GPR119CKS1B | |
| SCHEMBL31651803 | 0.81 | TLR9 (0.47) | TLR9SMPD3SUV39H2GBA1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | STAT6, STAT5B, STAT5A | TLR9 301/4885SMPD3 2793/4885SUV39H2 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.