Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.72 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.72 |
| ▸ | VAT1 | Q99536 | 1/20 | 0.72 |
| ▸ | RTN4 | Q9NQC3 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18128666 | 1.00 | KRAS (0.72) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL18128559 | 0.91 | KRAS (0.70) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL18128605 | 0.91 | KRAS (0.75) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL31658045 | 0.91 | KRAS (0.75) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL16636979 | 0.88 | KRAS (0.78) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL23105132 | 0.86 | KRAS (0.70) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL18128589 | 0.86 | KRAS (0.66) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL23092291 | 0.85 | KRAS (0.69) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL21371148 | 0.85 | KRAS (0.65) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL23093090 | 0.85 | KRAS (0.69) | KRASEGFRHMOX2CRYZVAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50490-E1 | Substituted quinazoline compounds and methods of use thereof | ARAXES PHARMA LLC (US) | 2025-07-15 | — | — | US | disclosed |