Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.93 |
| ▸ | EGFR | P00533 | 1/20 | 0.93 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.93 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.93 |
| ▸ | VAT1 | Q99536 | 1/20 | 0.93 |
| ▸ | RTN4 | Q9NQC3 | 1/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18128690 | 1.00 | KRAS (0.93) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL29373530 | 0.97 | KRAS (1.00) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL16637284 | 0.97 | KRAS (1.00) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL29379971 | 0.97 | KRAS (1.00) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL16647182 | 0.90 | KRAS (0.88) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL29765662 | 0.90 | KRAS (0.88) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL29766035 | 0.89 | KRAS (0.84) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL16646915 | 0.89 | KRAS (0.84) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL18842314 | 0.88 | KRAS (0.83) | KRASEGFRHMOX2CRYZVAT1 | |
| SCHEMBL21471922 | 0.87 | KRAS (0.82) | KRASEGFRHMOX2CRYZVAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50490-E1 | Substituted quinazoline compounds and methods of use thereof | ARAXES PHARMA LLC (US) | 2025-07-15 | — | — | US | disclosed |