⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355983 | 0.74 | HDAC8 (0.37) | — | |
| SCHEMBL3881120 | 0.70 | — | — | |
| SCHEMBL83774 | 0.70 | — | — | |
| SCHEMBL30159553 | 0.70 | — | — | |
| SCHEMBL27630930 | 0.70 | — | — | |
| SCHEMBL27274025 | 0.70 | — | — | |
| SCHEMBL19358691 | 0.70 | — | — | |
| SCHEMBL3825029 | 0.68 | HDAC8 (0.33) | — | |
| SCHEMBL1730333 | 0.68 | — | — | |
| SCHEMBL15772610 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116421507-A | Hair-loss-preventing and hair-growing composition and application thereof | 配方化妆品科技(广州)有限公司 | 2023-07-14 | — | — | CN | claimed |
| US-20050049232-A1 | Composition | LINDAU PAR (SE) | 2005-03-03 | — | — | US | claimed |
| EP-1463483-A1 | NEW COMPOSITION | Ponsus Pharma AB (SE) | 2004-10-06 | — | — | EP | claimed |
| US-20040116453-A1 | Synthesis and methods of use pyrimidine analogues and derivatives | SPECTRUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | claimed |
| EP-1334103-A2 | METHODS FOR TREATMENT OF DISEASE-INDUCED PERIPHERAL NEUROPATHY AND RELATED CONDITIONS | Neotherapeutics, Inc. (US) | 2003-08-13 | — | — | EP | claimed |
| EP-1334104-A2 | METHODS FOR TREATMENT OF DRUG-INDUCED PERIPHERAL NEUROPATHY AND RELATED CONDITIONS | Neotherapeutics, Inc. (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2003055454-A1 | NEW COMPOSITION | PONSUS PHARMA AB (SE) | 2003-07-10 | — | — | WO | claimed |
| US-20030055249-A1 | Synthesis and methods of use of pyrimidine analogues and derivatives | NEOTHERAPEUTICS, INC. | 2003-03-20 | — | — | US | claimed |
| WO-2003007963-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | NEOTHERAPEUTICS, INC. (US) | 2003-01-30 | — | — | WO | claimed |
| US-20020128264-A1 | Methods for treatment of conditions affected by activity of multidrug transporters | NEOTHERAPEUTICS, INC. | 2002-09-12 | — | — | US | claimed |
| EP-0378255-B1 | 2-Aminopyrimidinone derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1994-04-27 | — | — | EP | claimed |
| EP-0420707-B1 | Compositions to be used to reduce hair-loss and to induce and stimulate its growth, containing derivatives of 2-aminopyrimidine 3-oxide and new compounds derived from 2-aminopyrimidine 3-oxide | OREAL (FR) | 1993-12-15 | — | — | EP | claimed |
| CN-1044099-A | The 2-aminopyrimidinone derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1990-07-25 | — | — | CN | claimed |
| CN-1044094-A | 2-AMINOPYRIMIDINONE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1990-07-25 | — | — | CN | claimed |
| EP-0378254-A2 | 2-Aminopyrimidinone derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-18 | — | — | EP | claimed |
| EP-0378255-A2 | 2-Aminopyrimidinone derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-18 | — | — | EP | claimed |
| US-4523015-A | Process and nitroaminopyrimidone intermediates for histamine H2 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-11 | — | — | US | claimed |
| EP-0057546-A2 | Sulfonylurea N-oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-11 | — | — | EP | claimed |
| EP-0004793-B1 | 2-NITRO AMINOPYRIMIDONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE TO PREPARE 2-AMINOPYRIMIDONE DERIVATIVES WHICH HAVE HISTAMINE H2-ANTAGONIST ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-30 | — | — | EP | claimed |
| EP-0004793-A2 | 2-nitro aminopyrimidone derivatives, a process for their preparation and their use to prepare 2-aminopyrimidone derivatives which have histamine H2-antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-17 | — | — | EP | claimed |