Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864642 | 0.86 | PDE4B (0.39) | USP30PDE4BNR1H2NR1H3PTPN1 | |
| SCHEMBL17792475 | 0.85 | USP30 (0.44) | USP30BACE1NR1H2NR1H3RORC | |
| SCHEMBL24729177 | 0.83 | USP30 (0.38) | USP30PDE4BNR1H2NR1H3UCHL1 | |
| SCHEMBL3695799 | 0.83 | KDM1A (0.44) | USP30PDE4BNR1H2NR1H3RORC | |
| SCHEMBL29651255 | 0.83 | KDM1A (0.44) | USP30PDE4BNR1H2NR1H3RORC | |
| SCHEMBL8209429 | 0.82 | USP30 (0.40) | USP30BACE1NR1H2NR1H3RORC | |
| SCHEMBL31147949 | 0.82 | HDAC2 (0.46) | USP30PDE4BBACE1NR1H2NR1H3 | |
| SCHEMBL8484510 | 0.82 | MAPT (0.45) | PDE4BNR1H2NR1H3 | |
| SCHEMBL22864662 | 0.80 | CYP1A2 (0.40) | PDE4BNR1H2NR1H3PTPN1 | |
| SCHEMBL19608074 | 0.79 | USP30 (0.39) | USP30PDE4BNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |