Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661198 | 0.85 | MAPT (0.42) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL15146763 | 0.80 | MAPT (0.51) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL15140820 | 0.80 | MAPT (0.51) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL8353977 | 0.80 | MAPT (0.51) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL7235368 | 0.80 | MAPT (0.63) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL21430903 | 0.80 | MAPT (0.51) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL31661208 | 0.80 | MAPT (0.49) | MAPTHTTLMNAALDH1A1GAA | |
| SCHEMBL28718593 | 0.79 | MAPT (0.43) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL29433673 | 0.79 | MAPT (0.43) | MAPTHTTMAPK1LMNAALDH1A1 | |
| SCHEMBL31661170 | 0.78 | NAMPT (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |