Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598744 | 0.82 | GAA (0.59) | MAPTALDH1A1SMN1; SMN2GAATP53 | |
| SCHEMBL19284618 | 0.81 | SMN1; SMN2 (0.51) | MAPTALDH1A1SMN1; SMN2GAATP53 | |
| SCHEMBL31661198 | 0.80 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2GAAMAOB | |
| SCHEMBL31661176 | 0.80 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2GAATP53 | |
| SCHEMBL10069100 | 0.76 | BACE1 (0.49) | MAPTALDH1A1SMN1; SMN2GAABACE1 | |
| SCHEMBL30725419 | 0.76 | BACE1 (0.49) | MAPTALDH1A1SMN1; SMN2GAABACE1 | |
| SCHEMBL17080814 | 0.75 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2GAATP53 | |
| SCHEMBL14875495 | 0.74 | ADORA1 (0.43) | MAPTALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL8043687 | 0.74 | CKS1B (0.49) | CKS1BSKP1SKP2 | |
| SCHEMBL23218353 | 0.73 | MMP1 (0.43) | MAPTALDH1A1SMN1; SMN2GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |