Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661185 | 0.81 | CRBN (0.46) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL31701643 | 0.76 | PDK2 (0.54) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL30955807 | 0.74 | DDB1 (0.54) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL30726368 | 0.74 | DDB1 (0.54) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL26641479 | 0.74 | DDB1 (0.54) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL27371548 | 0.73 | PDK2 (0.52) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL27371048 | 0.73 | PDK2 (0.49) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL31661179 | 0.73 | CRBN (0.41) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL24379299 | 0.72 | PDK2 (0.48) | CRBNDDB1PDK2MAPTALDH1A1 | |
| SCHEMBL31661163 | 0.72 | CRBN (0.38) | CRBNDDB1PDK2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |