Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661163 | 0.80 | CRBN (0.38) | CRBNDDB1BACE1PDK2ALDH1A1 | |
| SCHEMBL31661185 | 0.80 | CRBN (0.46) | CRBNDDB1PDK2ALDH1A1LMNA | |
| SCHEMBL31661166 | 0.80 | CRBN (0.38) | CRBNDDB1BACE1PDK2ALDH1A1 | |
| SCHEMBL31661187 | 0.80 | ADRB1 (0.43) | — | |
| SCHEMBL5367156 | 0.75 | BACE1 (0.46) | BACE1PDK2ALDH1A1LMNAMAPT | |
| SCHEMBL31661181 | 0.73 | DDB1 (0.49) | CRBNDDB1MAPT | |
| SCHEMBL31661180 | 0.73 | CRBN (0.46) | CRBNDDB1PDK2ALDH1A1LMNA | |
| SCHEMBL5363056 | 0.72 | ALDH1A1 (0.44) | BACE1PDK2ALDH1A1LMNAMAPT | |
| SCHEMBL5373690 | 0.71 | BACE1 (0.50) | CRBNDDB1BACE1ALDH1A1LMNA | |
| SCHEMBL5366208 | 0.71 | NAMPT (0.47) | BACE1ALDH1A1LMNAMAPTMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |