Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31661177 | 0.99 | CRBN (0.37) | CRBNDDB1ADRB1BACE1HTR6 | |
| Sulfuric Acid SCHEMBL31661196 | 0.94 | PDK2 (0.36) | CRBNDDB1ADRB1BACE1HTR6 | |
| SCHEMBL31661169 | 0.78 | MAPKAPK2 (0.38) | CRBNDDB1ADRB1HTR6HTR3E | |
| SCHEMBL19586536 | 0.76 | CA9 (0.49) | BACE1CYP3A4MAPT | |
| SCHEMBL22018461 | 0.72 | BACE1 (0.54) | CRBNDDB1BACE1HTR6HTR1A | |
| Bromide SCHEMBL11198697 | 0.71 | CRBN (0.52) | CRBNDDB1ADRB1HTR6HTR3E | |
| SCHEMBL7274510 | 0.67 | CRBN (0.53) | CRBNDDB1ADRB1HTR6HTR3E | |
| SCHEMBL26641330 | 0.67 | CRBN (0.45) | CRBNDDB1ADRB1HTR6HTR3E | |
| SCHEMBL30955782 | 0.67 | CRBN (0.45) | CRBNDDB1ADRB1HTR6HTR3E | |
| SCHEMBL27039667 | 0.67 | CRBN (0.45) | CRBNDDB1ADRB1HTR6HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |