Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12012125 | 0.72 | MAPK1 (0.62) | MAPK1CYP1A2 | |
| Bromide SCHEMBL2334813 | 0.71 | MAPK1 (0.61) | MAPK1CYP1A2 | |
| SCHEMBL197826 | 0.71 | KMT2A (0.68) | SMN1; SMN2HTTALDH1A1KMT2AKDM4E | |
| Bromide SCHEMBL21996101 | 0.70 | KMT2A (0.66) | SMN1; SMN2HTTALDH1A1KMT2AKDM4E | |
| SCHEMBL1684384 | 0.70 | ALDH1A1 (0.64) | SMN1; SMN2HTTALDH1A1KMT2AKDM4E | |
| SCHEMBL6113039 | 0.70 | POLB (0.64) | SMN1; SMN2HTTALDH1A1POLBKMT2A | |
| Bromide SCHEMBL2337105 | 0.69 | ALDH1A1 (0.63) | SMN1; SMN2HTTALDH1A1POLBKMT2A | |
| SCHEMBL6533377 | 0.66 | POLB (0.47) | SMN1; SMN2HTTALDH1A1POLBKMT2A | |
| SCHEMBL6115382 | 0.66 | GSK3B (0.34) | ALDH1A1KMT2AKDM4EGSK3BMAPT | |
| SCHEMBL6112856 | 0.66 | ALDH1A1 (0.67) | SMN1; SMN2HTTALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |