Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017599 | 0.77 | ADORA1 (0.76) | ADORA1ADORA2ANPC1RAB9AMAPT | |
| SCHEMBL31661360 | 0.72 | HDAC6 (0.44) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL13962652 | 0.72 | NR1H4 (0.57) | ADORA1ADORA2ANPC1RAB9AMAPT | |
| SCHEMBL14959517 | 0.69 | HDAC6 (0.68) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL30792747 | 0.68 | ADORA1 (0.58) | ADORA1ADORA2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL317470 | 0.68 | MAPT (0.63) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL317471 | 0.68 | MAPT (0.63) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL317469 | 0.68 | MAPT (0.63) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL2104880 | 0.66 | HDAC6 (0.77) | ADORA1ADORA2ANPC1RAB9AMAPT | |
| SCHEMBL28784675 | 0.65 | HDAC6 (0.72) | NPC1RAB9AMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |