SCHEMBL317469

SCHEMBL317469

CC(=O)/C=C(/C)Nc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.63
GAA P10253 5/20 0.63
KDM4E B2RXH2 4/20 0.63
HPGD P15428 3/20 0.63
KMT2A Q03164 4/20 0.59
TDP1 Q9NUW8 2/20 0.59
HSD17B10 Q99714 3/20 0.59
NAPRT Q6XQN6 1/20 0.59
NPC1 O15118 6/20 0.57
RAB9A P51151 6/20 0.57
MEN1 O00255 2/20 0.57
THRB P10828 1/20 0.57
SMN1; SMN2 Q16637 5/20 0.55
TP53 P04637 3/20 0.55
MAPK1 P28482 3/20 0.55
ALDH1A1 P00352 3/20 0.55
PTGS2 P35354 1/20 0.53
EPHX1 P07099 2/20 0.52
TSHR P16473 1/20 0.52
EPHX2 P34913 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317470 1.00 MAPT (0.63) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL317471 1.00 MAPT (0.63) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL14482921 0.88 MAPT (0.63) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL1975201 0.88 MAPT (0.63) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL1975200 0.88 MAPT (0.63) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL11530335 0.86 PTGS2 (0.63) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL11530331 0.86 PTGS2 (0.63) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL15164801 0.82 MAPT (0.58) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL20291763 0.82 MAPT (0.58) MAPTGAAKDM4EHPGDKMT2A
SCHEMBL3078217 0.82 MAPT (0.81) MAPTGAAKDM4EHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397662-B1 PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND COPOLYMERIZATION SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-11 EP claimed
US-20180371115-A1 PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND CO-POLYMERIZATION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-12-27 US claimed
EP-3397662-A1 PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND COPOLYMERIZATION SABIC Global Technologies B.V. (NL) 2018-11-07 EP claimed
WO-2017114813-A1 PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND COPOLYMERIZATION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-06 WO claimed
EP-0214009-A2 Enaminones as potential prodrugs of primary and secondary amines MERCK & CO. INC. (US) 1987-03-11 EP claimed
US-11872548-B2 Oxo-nitrogenated iron complex, catalytic system comprising said oxo-nitrogenated iron complex and process for the (co)polymerization of conjugated dienes VERSALIS S.P.A. (IT) 2024-01-16 US disclosed
US-11872548-B2 Oxo-nitrogenated iron complex, catalytic system comprising said oxo-nitrogenated iron complex and process for the (co)polymerization of conjugated dienes VERSALIS S.P.A. (IT) 2024-01-16 US disclosed
EP-3397660-B1 PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND COPOLYMERIZATION SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-04-26 EP disclosed
US-20220123235-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-21 US disclosed
US-20210245145-A1 OXO-NITROGENATED IRON COMPLEX, CATALYTIC SYSTEM COMPRISING SAID OXO-NITROGENATED IRON COMPLEX AND PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES VERSALIS S.P.A. (IT) 2021-08-12 US disclosed
US-10730965-B2 Process for making a solid catalyst component for ethylene polymerization and co-polymerization SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-04 US disclosed
US-10654952-B2 Nitrogen titanium complex, catalytic system comprising said nitrogen titanium complex and process for the (co)polymerization of conjugated dienes VERSALIS S.P.A. (IT) 2020-05-19 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
EP-0214009-A2 Enaminones as potential prodrugs of primary and secondary amines MERCK & CO. INC. (US) 1987-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123235-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OXSR1, C1R MAPT 4337/4885GAA 3332/4885KDM4E 3581/4885
US-10654952-B2 Nitrogen titanium complex, catalytic system comprising said nitrogen titanium complex and process for the (co)polymerization of conjugated dienes CAT, NSFL1C, NCLN MAPT 3082/4885GAA 799/4885KDM4E 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.