Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 10/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735699 | 0.79 | LCK (0.63) | LCKALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL15186149 | 0.78 | LCK (0.53) | LCKCA1CA2PI4KBKDM4E | |
| SCHEMBL31661298 | 0.74 | LCK (0.46) | LCKCA1CA2ALDH1A1PI4KB | |
| SCHEMBL31661308 | 0.74 | LCK (0.46) | LCKCA1CA2ALDH1A1PI4KB | |
| SCHEMBL5408019 | 0.72 | LCK (0.46) | LCKCA1CA2PI4KB | |
| SCHEMBL31214308 | 0.71 | TSHR (0.49) | LCKALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL538349 | 0.71 | LCK (0.63) | LCKCA1CA2ALDH1A1PI4KB | |
| SCHEMBL773470 | 0.70 | LCK (0.66) | LCKCA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11103983 | 0.70 | PI4KB (0.43) | LCKCA1CA2PI4KBKDM4E | |
| SCHEMBL25261549 | 0.70 | LCK (0.53) | LCKCA1CA2PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |