Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661308 | 1.00 | LCK (0.46) | LCKALDH1A1RXFP1CA1CA2 | |
| SCHEMBL24735699 | 0.79 | LCK (0.63) | LCKALDH1A1RXFP1TSHR | |
| SCHEMBL7691178 | 0.78 | LCK (0.47) | LCKALDH1A1CA1CA2PI4KB | |
| SCHEMBL19371347 | 0.78 | LCK (0.47) | LCKALDH1A1CA1CA2PI4KB | |
| SCHEMBL15186149 | 0.78 | LCK (0.53) | LCKRXFP1CA1CA2PI4KB | |
| SCHEMBL25484165 | 0.75 | NPC1 (0.45) | LCKALDH1A1CA1CA2PI4KB | |
| SCHEMBL2717124 | 0.75 | LCK (0.45) | LCKALDH1A1PI4KBTSHRHPGD | |
| SCHEMBL2718161 | 0.75 | TSHR (0.51) | LCKALDH1A1TSHRHPGD | |
| SCHEMBL24434724 | 0.75 | NPC1 (0.55) | LCKCA1CA2PI4KB | |
| SCHEMBL31661322 | 0.74 | LCK (0.46) | LCKALDH1A1RXFP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |