Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661228 | 0.92 | MEN1 (0.65) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL31661254 | 0.85 | MEN1 (0.72) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL31661283 | 0.85 | MEN1 (0.67) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL31661318 | 0.82 | MEN1 (0.71) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL31661286 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL525388 | 0.74 | EGFR (0.58) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL31661216 | 0.72 | MEN1 (0.77) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL31661278 | 0.70 | MEN1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL525917 | 0.69 | RAB9A (0.50) | MEN1KMT2AMAPTSMN1; SMN2USP2 | |
| SCHEMBL30745699 | 0.69 | SLC2A1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |