Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 16/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582405 | 0.86 | RET (0.41) | KDM4ERET | |
| SCHEMBL31661213 | 0.81 | RET (0.40) | RETMKNK1 | |
| SCHEMBL17230357 | 0.75 | RET (0.39) | RETMKNK1 | |
| SCHEMBL21187103 | 0.75 | RET (0.40) | ALDH1A1HSD17B10RETMKNK1 | |
| SCHEMBL25477292 | 0.74 | RET (0.38) | RETMKNK1 | |
| SCHEMBL18665582 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL13991461 | 0.72 | NNMT (0.49) | ALDH1A1MKNK1 | |
| SCHEMBL24409052 | 0.72 | RET (0.40) | RETMKNK1 | |
| SCHEMBL19932703 | 0.71 | RET (0.41) | RETMKNK1 | |
| SCHEMBL27200507 | 0.71 | RET (0.36) | RETMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |